Increasing vaccination beyond childhood was one of the WHO challenges for 2020, including the vaccination of high-risk groups, among which we find health professionals and health science students. The WHO argues that to increase vaccine coverage, we should promote vaccination leadership through health professionals as a strategy to improve both vaccine acceptance and coverage, thereby strengthening Primary Care. Despite the education programs of nurses and other professionals, a variability in their knowledge is still found amongst the nurses themselves, so that the design of refresher programs for these professionals could improve their vaccine coverage and their patient’s as well. A patient’s confidence on her or his nurse and/or doctor has been associated to their final acceptance or rejection of vaccines. Health professionals are the most influential and main source of information about vaccines for the general population. Universities must become the leaders in vaccine education and training. It is therefore necessary to delve into and complete the nurses’ training on vaccines, to educate them about the risks at the individual level, and their decisive role as promoters of the vaccination strategy for the general population. Among the health professionals, Nurses (85.5%) must be better educated and trained on the subject of vaccines. Most of them considered that post-graduate education about vaccines should be provided by academic entities (universities, 62.7%). The main source of information was the family environment (65.6%). Hepatitis B (94.7%) and the Flu (89%) are the two main vaccines they should receive as health workers. The mean score obtained for knowledge about vaccines was 44.6 ± 4.3, and for attitudes towards vaccines, it was 37.2 ± 3.9. A total of 1122 students participated in the study. A cross-sectional study was performed through a questionnaire (55 items) provided to Nursing students at two Spanish universities. The objective of the present study was to determine the knowledge and attitudes of a group of university Nursing students about vaccines, as well as their sources of information and their education needs. Health professionals are the most influential and main sources of information about vaccines for the general population, as they are regarded as role models by patients and society.
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